5-HTP is short for 5-Hydroxytryptophan, which is an amino acid. As a transitional component in tryptophan metabolism, 5-HTP is also a compound which in the metabolic pathway precedes the monoamine neurotransmitter serotonin. As a dietary supplement, 5-HTP is suggested for use as an antidepressant, sleeping aid, but also as an appetite suppressant. Vitamin B6 helps 5-HTP decarboxylate into serotonin, with assistance of a lyase enzyme, namely the aromatic L amino acid decarboxylase. The theory is that 5-HTP, when ingested as a supplement, leads to increased serotonin production. While mainly being used as an appetite suppressant in the body building community, it also improves cognitive abilities, but also endurance and stamina. While there are some concerns in use of 5-HTP and MAO inhibitors in combination, sensitive users report only positive effects, that is why it was included in System-Six.

Betaine HCL, or betaine hydrochloride, is not an essential nutrient, but it helps in absorption of proteins, vitamin B12, iron and calcium and helps in the digestive tract with the protein and fat breaking up abilities. It is a supplemental source of hydrochloric acid, with a low pH level. Besides the obvious use against indigestion and heartburn, other uses have been proclaimed for betaine HCL, such as lowering the homocysteine level, helping with thyroid conditions and others. With progressing age, hydrochloric acid and digestive enzymes may decrease, with a poor digestion as a result. With betaine HCL, when taken at the beginning of a meal, proper digestion can be accomplished. Betaine HCL is most commonly provided with the addition of pepsin, a digestive enzyme.

Cayenne peppers are rich in vitamin A and C, calcium and other nutrients. They cure fever, colds and sore throats. They improve the digestive process. They protect the heart by strengthening arteries and regulating blood flow thus preventing heart attacks. External use reduces discomfort and swelling due to frostbite and joint pains by increasing blood flow to the area. Cayenne oil reduces toothaches effectively. Cayenne powder keeps hands and feet warm by improving blood circulation, when sprinkled into gloves or shoes. It is also known to reduce itching. A water-cayenne mixture helps to stop external bleeding. It reduces internal bleeding by even distribution of blood in the body. It also increases vigor and stamina. You must consult a physician before using cayenne for medicinal purposes.

Choline, sometimes called Choline Bitartrate, is an essential nutrient involved in many bodily actions such as the structure and function of cells and metabolic functions.

Chromium Picolinate increases the optimum levels of insulin while aiding in weight loss.

Citrus Aurantium, More commonly called "bitter orange", which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Garcinia Cambogia- Gambooge, a subtropical version of the Garcinia genus and native to Indonesia, is the local name for garcinia cambogia. It bears a pumpkin like yellow coloured fruit, which extract, together with the rind, is in India a curry condiment. Extracts are also being used in several herbal appetite suppressants, but also in some energy providing products and supplements. In the body building community, besides the weight loss properties of garcinia cambogia, the main component, hydroxycitric acid, or HCA, seems to increase the levels of lipolysis in athletes. HCA may even prove to be more effective in combined use with carnitine and pyruvate. In India, garcinia cambogia was traditionally used to treat edema, constipation, irregular menstruation and against intestinal parasites. Further uses include combating rheumatism and bowel related troubles.

Ginger Root refers to the rhizome of a plant called zingiber officinale that grows in moist and fertile tropical soil. Ginger is an underground stem extending to 12 inches above the ground. The ginger root has pungent phenol compounds and volatile oils. This is widely used as a medicine in Indian, Asian and Arabic herbal traditions. Ginger, in China is used to cure stomach upset, nausea and diarrhea since ancient times. Ginger is of great use to cure arthritis, diarrhea, Colic and heart conditions. Besides the medicinal value, Ginger is one of the indispensable ingredients as cooking spice and is also recommended to cure headaches, common cold, symptoms like flu and also painful menstrual periods. Ginger is widely used as medicine as it treats nausea, vomiting related to travel sickness, cancer chemotherapy and pregnancy. Though, there are effective medicines today, ginger root retain its position for its medicinal properties. It is also beneficial for heart disease as it reduces cholesterol and averts blood clotting. The ginger products are manufactured using dried or fresh ginger root and these are obtainable in extracts, capsules, tinctures and oils. Ginger is used in tea and in various drinks and foods.

Gotu Kola is one of the many common names given to the herbaceous annual plant called Centella asaitica. It is mainly found in countries like India, Sri lanka, Northern Australia, Malaysia, Iran, Indonesia, Melanesia and a few more on the Asian continent. This plant is used as a herb in traditional Chinese medicine and Ayurvedic medicine as well. It has slender stems that interconnect one plant to another. The leaves of this plant are long stalked and green in color. It has reniform leaves with rounded apices and is smooth in texture with palmately netted veins. The rootstocks which grows vertically down has rhizomes on it. Their color is creamish and are often covered with root hairs. The plant which is harvested manually matures in about three months, including the roots.

Green Tea Extract- For thousands of years, Green Tea has been used for the purpose of medicine in countries such as China and India. The leaves of the Camellia Sinensis plant are allowed to dry after being lightly steamed. The leaves are steamed as the properties of the plant are retained through this procedure. The extract has a number of varying health benefits, inclusive of properties that assist the body in fighting cancer and body protecting antioxidant effects. Green tea also offers protection against digestive and respiratory infections. It reduces health affecting LDL cholesterol, increases the levels of HDL cholesterol that is good for the body. Along with keeping control of the content of blood sugar in the body, it also helps burn fat in the body by boosting the metabolic rates.

Guarana has in recent times received widespread popularity because of an energy drink. It is actually a climbing plant in the family related to maple and is native to the Amazon region, predominantly in Brazil. It is a flowering plant with big leaves, but the fruit is the most prominent component, not bigger than a coffee bean. Guarana fruit has about the double content of caffeine when compared to the coffee bean. Besides the cognitive and fatigue reducing effects of caffeine, guarana displays also other interesting properties, such as the assistance in a weight loss program; namely, guarana affects the perception of the satiation, making the person feel full sooner. Further antioxidant and antibacterial effects have been noted as well. In combination with linoleic acid, guarana has shown fat cell reduction effects in mice.

Inositol - The precise role of Inositol is unknown. Animals deficient in inositol grow poorly and show hair loss. iI occurs naturally in fruits and cereals.

L-Carnitine is yet another weight loss supplement that also is an antioxidant and has effects on male infertility, diabetes, and bone mass and fatty acid metabolism.

L-Tyrosine is a protein non-essential building block Although non-essential it is important for the structure of body proteins. It has a direct effect on neurotransmitters.

Niacin, also called Vitamin B3, is a water-soluble vitamin needed for the conversion of food into energy so that it may be used by the body. Niacin also helps metabolize protein, sugar and fat.

Pantothenic Acid is actually a part of the Vitamin B complex, namely Vitamin B5 and is deemed an essential nutrient. It has a critical function in the synthesis and metabolism of core nutrients, such as fats, proteins and carbohydrates, and it forms the coenzyme – A, also called CoA, most notable for the role in oxidation and synthesis of fatty acids and pyruvate. The Greek origin of the name Pantothenic Acid already states that this Vitamin is found nearly everywhere, with prominent amounts in eggs, meat, legumes and whole grain cereals. In health and fitness circles the dietary supplement is very popular for its energy producing role, but also for the ATP process and for the maintenance of cholesterol and triglycerides levels in the body.

Riboflavin, an easily absorbed micronutrient, is also known by the name of Vitamin B2. It plays a key role in maintaining the health of animals as well as humans. A wide variety if cellular processes require this vitamin. It plays a key role in energy metabolism, just like other B vitamins. It is the kind of micronutrient which required for the metabolism of proteins, carbohydrates, fats and ketone bodies. There are a lot of food products that are a good source of Vitamin B2. Matured soybeans, yeast, mushroom, livers, kidneys, leafy vegetables, milk, cheese, almonds are such products that are rich in this vitamin. But riboflavin does get destroyed if exposed to light. Riboflavin is a non toxic vitamin. Hence, there is no harm in taking it orally.

Selenium is a trace mineral that plays an important role in several metabolic pathways such as glutathione-peroxidise pathway. Selenium works with Vitamin E which gives its strong antioxidant effects and improves the immune system. It protects the body from prematurely aging. It also help prevent free radical damages that may cause heart diseases and cancer. It is essential in the proper function of the thyroid hormones, and promotes efficient metabolism. It is also beneficial in the reproductive health particularly of men because it facilitates in the sperm production, and prevents infertility. Selenium also helps reduce inflammation which is beneficial to those with rheumatism to reduce pain.

Spirulina, unicellular blue - green algae, is one of the earliest photosynthetic life forms on earth. This micro-organism is rich in vegetable proteins, vitamins, minerals, carbohydrates, enzymes, lipids, phytochemicals and essential amino acids. Since it is very easily digestible and provides a balance of necessary nutrients, it has become a potential source of probiotic, whole food. For instance, the blue colored pigments called phycocyanin are known to combat cancer. For these reasons, Spirulina is also considered to be a beneficial biochemical and medical resource. Through ages, the alga has been widely used for its nutritional properties by the indigenous people of North Africa and Mexico. But now, Spirulina is used in dietary supplements also. Commercial preparations of Spirulina are available in the form of powder, capsules, and tablets.