5-HTP is short for 5-Hydroxytryptophan, which is an amino acid. As a transitional component in tryptophan metabolism, 5-HTP is also a compound which in the metabolic pathway precedes the monoamine neurotransmitter serotonin. As a dietary supplement, 5-HTP is suggested for use as an antidepressant, sleeping aid, but also as an appetite suppressant. Vitamin B6 helps 5-HTP decarboxylate into serotonin, with assistance of a lyase enzyme, namely the aromatic L amino acid decarboxylase. The theory is that 5-HTP, when ingested as a supplement, leads to increased serotonin production. While mainly being used as an appetite suppressant in the body building community, it also improves cognitive abilities, but also endurance and stamina. While there are some concerns in use of 5-HTP and MAO inhibitors in combination, sensitive users report only positive effects, that is why it was included in System-Six.

Betaine HCL, or betaine hydrochloride, is not an essential nutrient, but it helps in absorption of proteins, vitamin B12, iron and calcium and helps in the digestive tract with the protein and fat breaking up abilities. It is a supplemental source of hydrochloric acid, with a low pH level. Besides the obvious use against indigestion and heartburn, other uses have been proclaimed for betaine HCL, such as lowering the homocysteine level, helping with thyroid conditions and others. With progressing age, hydrochloric acid and digestive enzymes may decrease, with a poor digestion as a result. With betaine HCL, when taken at the beginning of a meal, proper digestion can be accomplished. Betaine HCL is most commonly provided with the addition of pepsin, a digestive enzyme.

Cayenne also called as Capsicum frutescens is known for its medicinal properties. Cayenne in powder form is said to be more effective because the healing process starts from the mouth to the tongue, as opposed to capsule form. It is a natural pain killer commonly used in treating pains caused by arthritis, and muscle aches. It increases the metabolism that aids in burning of fats. It improves immune function that protects against infections. It is also a potent antioxidant because of its vitamin E and Vitamin C contents. It protects the heart from cardiovascular diseases. It is used as a tonic for the kidney, spleen, stomach and lungs. It is also used to treat psoriasis, bunions, and muscle pains.

Choline was discovered in 1864 by Andreas Strecker, Choline is a water soluble organic compound. This nutrient is found in the neurotransmitter acetylcholine and lipids which make up cell membranes. Choline is a member of the Vitamin B Complex group and it is generally required for physiological purposes like structuring of cell membranes, as a precursor molecule for neurotransmitter acetylcholine and to protect the livers from accumulation of fat. Besides the infant or fetus brain development, choline can also prevent memory loss caused due to aging. Your homocysteine levels related to cardiovascular diseases and cholesterol can be lowered by it. The recommended intake of choline which is found in peanut butter, beef liver, cauliflower and almonds is 550 mg for men and 425 mg for women.

Chromium Picolinate - The popular nutritional supplement, which has been invented to treat chromium deficiency, is also a popular weight loss and muscle growth product. Due to the chromium role it plays in sugar and lipid metabolism in humans, it has been deemed helpful as a supplement, in particular with the body building communities. The argument is that chromium picolinate improves the uptake of glucose by enhancing the effect insulin has in the body, providing better blood circulation. Bad dietary habits, in particular in the United States, have lead to the population verging on the brim of chromium deficiency. Body Building aficionados really require a wholly balanced diet, which in turn requires adequate amounts of chromium be present in the metabolism, even more so if the individual is practicing a serious exercise program.

Citrus Aurantium, More commonly called "bitter orange", which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Garcinia Cambogia is a natural extract that comes from a fruit located in India and is prominent in a plethora of different natural weight loss products.

Ginger Root is a dietary supplement that is not only used as a spice but has had a positive effect on some types of arthritis and raynauds disease.

Gotu Kola, also known as hydrocotyle, centella asiatica or indian pennywort. Gota Kola is commonly used for wound healing, and improved mental function. The most active constituents are the triterpene saponins, which include asiaticoside, brahmoside, brahminoside, brahmaic acid and madecassoside.

Green Tea Extract is currently being promoted by the health conscious community as a weight loss product, which does not do this incredible concoction of helpful ingredients justice. Many green tea extracts nowadays exclude caffeine, to avoid the associated side effects and lower the ingestion of this legal addictive stimulant. The main characteristic of the green tea extract should be the antioxidative effect, which surpasses Vitamin C twentyfold. But the other traits are not to be forgotten, it is anti-inflammatory, anti-carcinogen and anti-radiation. The unique combination of green tea catechins, derivatives of apicatechin, and flavonoids, which belong to the same family, are proven scavengers of free radicals and an unavoidable addition to any dietary supplement combination, body building or weight loss as the target objective.

Guarana is not only a dietary supplement but also an energy booster as well as it has a high concentration of caffeine.

Inositol works as a second messenger within our bodies to stimulate the release of calcium from its storage place within our bodies; it allows the transmission of neural signals to be enhanced.

L-Carnitine allows our bodies the opportunity to utilize fat as our main source of energy instead of simply for storage.

L-Tyrosine is an amino acid that is nonessential. It is synthesized from the body from phenylalanine which is also an amino acid. L-Tyrosine has the power to have an effect on the neurotransmitters and this affects various health conditions including depression, mood disorders and Parkinson’s disease. Many such studies have proved that L-Tyrosine helps people having depression. It acts as a precursor and eases the effects of psychosocial, environmental and physical stress. L-Tyrosine turns into melanin by the skin cells and the dark pigment prevents the ultraviolet light from affecting. The thyroid hormones playing a significant role in the process of the body also contain tyrosine. L-Tyrosine is commonly found in all the dairy products, fish, oats, wheat, meat and also in all other protein containing foods. This is also found to be beneficial for people trying to withdraw alcohol. L-Tyrosine has not exhibited severe side effects, yet taking it should be recommended by doctors.

Niacin is an essential B vitamin, in cellular energy used for the promotion of healthy cardiovascular function, nervous system function, and immune function. Niacin nutritionally manages cholesterol levels already within the normal range. Also known as vitamin B3, niacin is one of a complex of B vitamins that are essential for good health. Niacin is so-called nicotinic acid, known also as nicotinamide. It helps regulate blood sugar and also works at cellular level protecting the skin and enhances the digestive system. And being an originator of the amino acid tryptophan, it can be made by tryptophan in the body. It’s also a coenzyme playing an important role in body metabolism. Supplements of vitamin B3 are also known to reduce levels of bad cholesterol and increase good cholesterol in the blood.

Pantothenic Acid is thought to reduce lactic acid accumulation in athletes, may improve oxygen utilization efficiency, and is believed to improve the body's ability to heal and possibly help in reducing acne

Riboflavin, an easily absorbed micronutrient, is also known by the name of Vitamin B2. It plays a key role in maintaining the health of animals as well as humans. A wide variety if cellular processes require this vitamin. It plays a key role in energy metabolism, just like other B vitamins. It is the kind of micronutrient which required for the metabolism of proteins, carbohydrates, fats and ketone bodies. There are a lot of food products that are a good source of Vitamin B2. Matured soybeans, yeast, mushroom, livers, kidneys, leafy vegetables, milk, cheese, almonds are such products that are rich in this vitamin. But riboflavin does get destroyed if exposed to light. Riboflavin is a non toxic vitamin. Hence, there is no harm in taking it orally.

Selenium , an essential mineral that is toxic at high dosages. Selenium plays an important function in the antioxidant enzymes that protect cells against free radicals. Selenium also promotes proper thyroid hormone metabolism.

Spirulina, unicellular blue - green algae, is one of the earliest photosynthetic life forms on earth. This micro-organism is rich in vegetable proteins, vitamins, minerals, carbohydrates, enzymes, lipids, phytochemicals and essential amino acids. Since it is very easily digestible and provides a balance of necessary nutrients, it has become a potential source of probiotic, whole food. For instance, the blue colored pigments called phycocyanin are known to combat cancer. For these reasons, Spirulina is also considered to be a beneficial biochemical and medical resource. Through ages, the alga has been widely used for its nutritional properties by the indigenous people of North Africa and Mexico. But now, Spirulina is used in dietary supplements also. Commercial preparations of Spirulina are available in the form of powder, capsules, and tablets.