Alpha Lipoic Acid is said to be a powerful antioxidant that aids in the neutralization of free radicals i.e unstable molecules that cause damage, within the body. It is easily absorbed by the gut whether taken in food or as a supplement and is used to detoxify the liver by increasing levels of glutathione which then go on to dissolve toxic substances contained in liver cells. It helps vitamins such as C and E be more efficient and is particularly efficient at alleviating the symptoms of glaucoma and generally protecting the lens and retina from degenerative processes. It can be especially beneficial for those with raised blood sugar levels as in diabetes, anyone with a high level of cholesterol or who has hardening of the arteries or early stage cataracts.

Bioperine or black pepper, which is a common spice, has medicinal properties. It is a tropical plant and India is the largest producer of Piper Nigrum. It possesses anti-bacterial and anti-inflammatory properties. It acts as an antioxidant agent also. Black Pepper contains essential oil, which acts against intestinal flatulence and also stimulates sweating and urination. The essential oil found in Piper Nigrum stimulates stomach cells to produce HCl acid, which helps in digestion. Piper Nigrum also helps in absorption of certain essential micronutrients like coenzyme Q-10, beta-carotene and EGCG. Pepper has its contribution in Ayurvedic medicines also. Pepper seeds are used to prepare sinusitis relieving medicines. It also used for sore throat and dry cough.

Caffeine, a central nervous system stimulant used in Thermoloid as an aid to stay awake, for mental alertness due to fatigue or, in combination with other ingredients for pain relief, and as a power and energy accelerate. Caffeine is available alone as a non-prescription drug over the counter medication, in combination with other non-prescription drugs, and in prescription drug combinations for relief of pain and headache. Like Ephedra, caffeine acts to increase mental alertness while providing additional energy for weight loss and exercise training. Caffeine is more than a stimulant as it goes deep into muscles to provide long lasting power while delaying the onset of muscle fatigue. Also great before working out, caffeine fights fatigue and helps you get ready for your workout. For dieters feeling sluggish that need just a little something extra to get them through the day, caffeine is the obvious no-calorie stimulant solution. Many products containing caffeine anhydrous contain as much caffeine as one or two cups of coffee. It is recommended to limit the use of caffeine containing medications, foods, or beverages while taking caffeine supplements as excess caffeine intake may cause nervousness, irritability, sleeplessness and occasional rapid heart beat.

Citrus Aurantium, More commonly called "bitter orange", which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Green Tea Extract, a bioflavonoid rich, potent extract used primarily for fighting free radicals. It contains a high content of polyphenols, which are a class of bioflavonoids. Green tea extract contains a potent antioxidant, EGCG, which is over 200 times more powerful than vitamin E in neutralizing the pro-oxidants and free radicals that attack lipids in the brain. Green tea extract helps with thermogenesis and aids in the metabolism of fat. Green Tea has been used for years as a powerful antioxidant, it may also be helpful in shedding fat. The most obvious benefit to dieters is that it works without increasing the heart rate most often found in diet aids. The increased heart rate leaves dieters jittery and eventually, most dieters stop using the supplement and gain weight back. Now through using green tea extract, dieters get the weight loss benefits without any of the jittery effects, especially in obese individuals with hypertension and other cardiovascular complications.

Guarana contains a significant amount of guaranine, a substance that is similar to caffeine found in coffee beans. It helps stimulate the adrenal glands and increase the production and release of hormones such as epinephrine, norepinephrine (adrenaline), and dopamine. This helps the metabolism of the body that enhances fat loss, and increases energy and endurance. It helps the body burn the fats to be used for energy. It aids in fighting stress, weakness and fatigue. As a stimulant, it also improves mental alertness, clarity, focus, concentration, and memory retention. Guarana also also improves the libido or sex drive in both men and women. Guarana also contains tannins that help prevent diarrhea and soothes the digestive system.

L-Carnitine is yet another weight loss supplement that also is an antioxidant and has effects on male infertility, diabetes, and bone mass and fatty acid metabolism.

Synthetic Guggulsterones improve the metabolism by increasing the thyroid hormones that influences the triiodothyronine (T3) hormones. It also activate the lypolytic enzymes the helps the burning of fats. Synthetic Guggulsterones is effective for weight loss without raising the heart rate. It also helps maintain the ideal cholesterol level within the normal range. It decreases the LDL cholesterol and triglyceride (TG) levels. Synthetic Guggulsterones also acts as a potent anti-inflammatory agent because of its myrrhanol A content. It also helps reduce acne because it contains tetracycline that is commonly used as an antibiotic in treating acne. It also reduces oxidative stress by decreasing the lipid peroxidation.

White Willow Bark, less commonly known as salix alba, is extracted from a plant native to Europe and parts of Asia. The great physician Hippocrates first mentioned the use of White willow extract in his writings in 5th century BC and it has been touted as a powerful supplement for several different uses ever since. It is commonly used as a pain reliever (particularly for back pain and arthritis), fever reducer, and inflammation reducer. Although aspirin was eventually invented using the same base as White willow extract, many purists and natural health enthusiasts prefer to use White willow extract, which is considered to be nature’s aspirin.

Yerba Matte, actually yerba maté, as it is called in Brazil, or Ilex paraguariensis in Latin, is a small tree or a shrub which can grow to fifteen meters. It is found naturally in South America, mainly in south of Brazil, Argentina, Paraguay, Uruguay and Chile. Foliage is evergreen, and the flowers are rather small, additionally there is a smallish fruit of red color. A tea like brewing in warm water, not boiling, is a popular drink in the native area, similar social gathering is common, akin to tea time practice in the United Kingdom. Yerba matte has several xanthines alkaloids which are related to caffeine, but although chemically identical to caffeine the mate xanthine cocktail provides different results, for instance it relaxes smooth muscle tissue and stimulates heart tissue. Yerba Matte is a potent ingredient in Thermoloid.